Genome Organization

Genome organization is the hierarchical arrangement of DNA elements and chromosomes across multiple spatial scales from linear molecular sequences to three-dimensional conformations within the nucleus.

15.3K

Publications

1.3M

Citations

43.5K

Authors

4.7K

Institutions

Publications per year

2017–2026

1.5K

Variants

Genomic Organization

Parents

Molecular BiologyMolecular Genetics

Children

Centromere OrganizationChromatinChromosome ArchitectureChromosome CondensationChromosome StructureChromosome TerritoriesDna LoopingDna PackagingGenome CompartmentalizationGenome Packaging

Publications

15.3K

An integrated encyclopedia of DNA elements in the human genome

Nature · 2012 · 19.4K citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

The Sequence of the Human Genome

J. Craig Venter, Mark D. Adams, Eugene W. Myers et al. · Science · 2001 · 13.7K citations

Life Sciences, Genetics, Molecular Genetics +11

Sequence and organization of the human mitochondrial genome

Stephen K. Anderson, Alan T. Bankier, B. G. Barrell et al. · Nature · 1981 · 9.7K citations

Medicine, Genetics, Molecular Genetics +12

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

Erez Lieberman-Aiden, Nynke L. van Berkum, Louise Williams et al. · Science · 2009 · 9.6K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Topological domains in mammalian genomes identified by analysis of chromatin interactions

Jesse R. Dixon, Siddarth Selvaraj, Feng Yue et al. · Nature · 2012 · 7.4K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

1–5 of 15.3K

Authors

43.5K

JD
Job Dekker
University of Massachusetts Chan Medical School, United States
59 publications · 34.7K citations
48
h-index
GB
Giorgio Bernardi
Institut Jacques Monod, France
74 publications · 6.7K citations
45
h-index
EE
Evan E. Eichler
University of Washington, United States
52 publications · 14.7K citations
40
h-index
JG
Joseph G. Gall
Department of Embryology, United States
48 publications · 5.9K citations
36
h-index
HF
Huntington F. Willard
Case Western Reserve University, United States
40 publications · 6.3K citations
35
h-index

1–5 of 43.5K

Institutions

4.7K

1–8 of 4.7K

Venues

Cell
342 publications · 96.9K citations
172
h-index
Nature
419 publications · 158K citations
168
h-index
Proceedings of the National Academy of Sciences
PNAS · 683 publications · 79.8K citations
148
h-index
Science
209 publications · 77.4K citations
111
h-index
Journal of Molecular Biology
JMB · 479 publications · 45.3K citations
105
h-index

1–5

See also Genome Organization
Chromatin Architecture	Chromosome Territories Topologically Associating Domains Chromatin Loops A/b Chromatin Compartments Loop Extrusion Phase Separation Enhancer-promoter Interactions
Structural Scales	Primary Structures Secondary Structure Tertiary Structure Chromatin Loops Topologically Associating Domains A/b Chromatin Compartments Chromosome Territories
Measurement Techniques	Chromosome Conformation Capture Circular Chromosome Conformation Capture Hi-c In Situ Hybridization Immunofluorescence Imaging Micro-c
Nuclear Context	Chromatin Chromosome Territories Radial Chromosome Arrangement Nuclear Lamina Lamin-associated Domains Nuclear Shapes Nuclear Bodies Nuclear Speckles Heterochromatin Organization