Concepedia

Polycomb-mediated Chromatin Repression

Polycomb-Mediated Chromatin Repression is a gene regulatory mechanism, belonging to the class of epigenetic silencing processes, that is distinguished by the targeted compaction of chromatin and transcriptional repression orchestrated by Polycomb group proteins through histone modifications and nucleosome remodeling.

379

Publications

52.5K

Citations

2.7K

Authors

761

Institutions

Publications per year

2017–2026

134

Parents

Publications

379

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

Miao-Chih Tsai, Ohad Manor, Yue Wan et al. · Science · 2010 · 3.3K citations · Full text

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Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

Ahmad M. Khalil, Mitchell Guttman, Maite Huarte et al. · Proceedings of the National Academy of Sciences · 2009 · 2.9K citations · Full text

, , +17

Drosophila Enhancer of Zeste/ESC Complexes Have a Histone H3 Methyltransferase Activity that Marks Chromosomal Polycomb Sites

Birgit Czermin, Raffaella Melfi, Donna McCabe et al. · Cell · 2002 · 1.5K citations · Full text

, , +17

Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a

Kyoko L. Yap, SiDe Li, Ana M. Muñoz-Cabello et al. · Molecular Cell · 2010 · 1.4K citations · Full text

, , +17

Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains

Wolfgang Fischle, Yanming Wang, Steven Jacobs et al. · Genes & Development · 2003 · 979 citations · Full text

, , +17

1–5 of 379

Authors

2.7K

  1. RP
    Renato Paro

    Heidelberg University, Germany

    9 publications · 1.3K citations

    9

    h-index

  2. HK
    Haruhiko Koseki

    RIKEN Center for Integrative Medical Sciences, Japan

    9 publications · 1.5K citations

    9

    h-index

  3. RM
    Raphaël Margueron

    Inserm, France

    8 publications · 1.6K citations

    8

    h-index

  4. DP
    Diego Pasini

    European Institute of Oncology, Italy

    8 publications · 1.6K citations

    8

    h-index

  5. MV
    Maarten van Lohuizen

    The Netherlands Cancer Institute, Netherlands

    7 publications · 1.8K citations

    7

    h-index

1–5 of 2.7K

Institutions

761

  1. Harvard University

    Cambridge, United States

    27 h-index

    132 publications

    36.6K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    22 h-index

    84 publications

    28.1K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    21 h-index

    140 publications

    13.9K citations

  4. Inserm

    Paris, France

    12 h-index

    77 publications

    5.1K citations

  5. National Institutes of Health

    Bethesda, United States

    11 h-index

    46 publications

    5K citations

  6. RIKEN Center for Integrative Medical Sciences

    Yokohama, Japan

    11 h-index

    44 publications

    5.1K citations

  7. Massachusetts General Hospital

    Boston, United States

    11 h-index

    52 publications

    9.4K citations

  8. University of Pennsylvania

    Philadelphia, United States

    11 h-index

    45 publications

    3.9K citations

1–8 of 761

Venues

  1. Nature Communications

    22 publications · 1.8K citations

    20

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 19 publications · 5.3K citations

    19

    h-index

  3. Molecular Cell

    18 publications · 4.1K citations

    18

    h-index

  4. Genes & Development

    15 publications · 4.4K citations

    15

    h-index

  5. Cell Reports

    15 publications · 1.5K citations

    15

    h-index

1–5