Leukemia · 2019 · 115 citations · 55 references
MedicineHematologyMolecular MedicineNeoplasiaCellular Responses To HypoxiaHematologic MalignanciesHematopoietic NeoplasmsHypoxia AdaptationMyeloproliferative NeoplasmsHif-1 SignalingHypoxia-inducible Factor SignalingJak2 MutationsJak2 V617f MutationMyeloproliferative Neoplasm TherapyMyeloproliferative Neoplasm TreatmentTherapeutic Target Identification
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A Gain-of-Function Mutation of <i>JAK2</i> in Myeloproliferative Disorders
Róbert Královics, Francesco Passamonti, Andreas Buser et al. · New England Journal of Medicine · 2005 · 3.5K citations · Full text
Life Sciences, Genetics, Hematology +15
Somatic Mutations of Calreticulin in Myeloproliferative Neoplasms
Thorsten Klampfl, Heinz Gisslinger, Ashot S. Harutyunyan et al. · New England Journal of Medicine · 2013 · 2K citations · Full text
Medicine, Genetics, Hematology +14
Placebo-Controlled Phase 3 Study of Oral BG-12 for Relapsing Multiple Sclerosis
Ralf Gold, Ludwig Kappos, Douglas L. Arnold et al. · New England Journal of Medicine · 2012 · 1.7K citations · Full text
Medicine, Neurology, Pharmacotherapy +17
MPLW515L Is a Novel Somatic Activating Mutation in Myelofibrosis with Myeloid Metaplasia
Yana Pikman, Benjamin H. Lee, Thomas Mercher et al. · PLoS Medicine · 2006 · 1.4K citations · Full text
Life Sciences, Genetics, Hematology +14
Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells
Keiyo Takubo, Nobuhito Goda, Wakako Yamada et al. · Cell stem cell · 2010 · 864 citations · Full text