Hypoxia-inducible factor 1 (HIF-1) is a new therapeutic target in JAK2V617F-positive myeloproliferative neoplasms

Julian Baumeister, Nicolas Chatain, Annika Hubrich, +14

Leukemia

Hematological MalignancyNew Therapeutic TargetHypoxia (Medicine)ImmunologyHematology +6

The role of Nav1.7 in human nociceptors: insights from human induced pluripotent stem cell–derived sensory neurons of erythromelalgia patients

Jannis Meents, Elisângela Bressan, Stephanie Sontag, +20

Pain

The Polycomb Protein Ezh2 Impacts on Induced Pluripotent Stem Cell Generation

Xiaolei Ding, Xiaoying Wang, Stephanie Sontag, +4

Stem Cells and Development

Ezh2 MrnaExtensive Chromatin ReorganizationStem Cell BiologyEpigeneticsCell Regulation +17

Modelling IRF8 Deficient Human Hematopoiesis and Dendritic Cell Development with Engineered iPS Cells

Stephanie Sontag, Malrun Förster, Jie Qin, +7

Stem Cells

Women who take n-3 long-chain polyunsaturated fatty acid supplements during pregnancy and lactation meet the recommended intake

Xiaoming Jia, Mohammadreza Pakseresht, Nour Wattar, +6

Applied Physiology Nutrition and Metabolism

To Clone or Not to Clone? Induced Pluripotent Stem Cells Can Be Generated in Bulk Culture

Charlotte A. Willmann, Hatim Hemeda, Lisa A. Pieper, +9

PLoS ONE

Physical activity specifically evokes release of cell-free DNA from granulocytes thereby affecting liquid biopsy

Elmo W. I. Neuberger, Stephanie Sontag, Alexandra Brahmer, +4

Clinical Epigenetics

Human DC3 Antigen Presenting Dendritic Cells From Induced Pluripotent Stem Cells

Taiki Satoh, Marcelo A. S. Toledo, Janik Boehnke, +11

Frontiers in Cell and Developmental Biology

Nintedanib targets KIT D816V neoplastic cells derived from induced pluripotent stem cells of systemic mastocytosis

Marcelo A. S. Toledo, Malrun Gatz, Stephanie Sontag, +26

Blood

Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF

Kai Ling Liang, Juliette Roels, Marieke Lavaert, +19

Nature Immunology

Irf8-driven Transmembrane TnfSignal TransductionT-regulatory CellImmunologyT Cell Immunity +5