The Challenge of Variability in Chimeric Antigen Receptor T Cell Manufacturing

Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia

Joseph A. Fraietta, Simon F. Lacey, Elena J. Orlando et al. · Nature Medicine · 2018 · 1.8K citations · Full text

Life Sciences, Immunology, Oncology +16

Suppression of T-cell functions by human granulocyte arginase

Markus Munder · Blood · 2006 · 415 citations · Full text

Life Sciences, Cell Biology, Immunology +13

Early memory phenotypes drive T cell proliferation in patients with pediatric malignancies

Nathan Singh, Jessica Perazzelli, Stephan A. Grupp et al. · Science Translational Medicine · 2016 · 297 citations

Medicine, Immunology, Oncology +17

Citrate pharmacokinetics and metabolism in cirrhotic and noncirrhotic critically ill patients

Ludwig Kramer, Edith Bauer, Christian Joukhadar et al. · Critical Care Medicine · 2003 · 267 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Age-Related Decline in Primary CD8+ T Cell Responses Is Associated with the Development of Senescence in Virtual Memory CD8+ T Cells

Kylie M. Quinn, Annette Fox, Kim L. Harland et al. · Cell Reports · 2018 · 265 citations · Full text

Education, Cell Biology, Immunology +14