Jessica Perazzelli

Convergence of Acquired Mutations and Alternative Splicing of <i>CD19</i> Enables Resistance to CART-19 Immunotherapy

Elena Sotillo, David M. Barrett, Kathryn L. Black et al. · Cancer Discovery · 2015 · 1.2K citations · Full text

Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies

Marco Ruella, David M. Barrett, Saad S. Kenderian et al. · Journal of Clinical Investigation · 2016 · 549 citations · Full text

Mixed-phenotype Acute Leukemia, Immunology, Immunoediting +22

Early memory phenotypes drive T cell proliferation in patients with pediatric malignancies

Nathan Singh, Jessica Perazzelli, Stephan A. Grupp et al. · Science Translational Medicine · 2016 · 286 citations

T Cell Therapy, Hematological Malignancy, T Cell Populations +15

Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells

Nathan Singh, Noelle V. Frey, Boris Engels et al. · Nature Medicine · 2021 · 189 citations · Full text

Antigen-independent Activation, Autoimmune Disease, Immunology +8

Purification of mRNA Encoding Chimeric Antigen Receptor Is Critical for Generation of a Robust T-Cell Response

Jessica Foster, Namrata Choudhari, Jessica Perazzelli et al. · Human Gene Therapy · 2018 · 127 citations · Full text

Adaptive Immune System, T-regulatory Cell, Immunology +17