TOPK inhibits autophagy by phosphorylating ULK1 and promotes glioma resistance to TMZ

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Joungmok Kim, Mondira Kundu, Benoı̂t Viollet et al. · Nature Cell Biology · 2011 · 6.8K citations · Full text

Mtor Regulate Autophagy, Mitophagy, Cell Autophagy +10

Oncogenic Signaling Pathways in The Cancer Genome Atlas

Francisco Sánchez-Vega, Marco Mina, Joshua Armenia et al. · Cell · 2018 · 3.2K citations · Full text

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

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Mitophagy, Environmental Stress, Cell Death +18

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion

Cristovão M. Sousa, Douglas E. Biancur, Xiaoxu Wang et al. · Nature · 2016 · 1.1K citations · Full text

Cell Autophagy, Autophagic Alanine Secretion, Pancreatic Cancer +8

mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6

Francesca Nazio, Flavie Strappazzon, Manuela Antonioli et al. · Nature Cell Biology · 2013 · 762 citations

Cell Autophagy, Mitophagy, Signal Transduction +10