CRISPR/Cas9-mediated myostatin disruption enhances muscle mass in the olive flounder Paralichthys olivaceus

Regulation of skeletal muscle mass in mice by a new TGF-p superfamily member

Alexandra C. McPherron, Ann M. Lawler, Se‐Jin Lee · Nature · 1997 · 3.9K citations

Mechanobiology, Muscle Function, Molecular Physiology +11

Engineered CRISPR-Cas9 nucleases with altered PAM specificities

Benjamin P. Kleinstiver, Michelle S. Prew, Shengdar Q. Tsai et al. · Nature · 2015 · 1.6K citations · Full text

Engineering, Synthetic Biology, Genetic Engineering +8

Myostatin Mutation Associated with Gross Muscle Hypertrophy in a Child

Markus Schuelke, Kathryn R. Wagner, Leslie E. Stolz et al. · New England Journal of Medicine · 2004 · 1.4K citations · Full text

A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep

Alex Clop, Fabienne Marcq, Haruko Takeda et al. · Nature Genetics · 2006 · 1.2K citations

Developmental Biology, Skeletal Muscle, Genetics +7

Mutations in <i>myostatin</i> (<i>GDF8</i>) in Double-Muscled Belgian Blue and Piedmontese Cattle

Ravi Kambadur, Mridula Sharma, Timothy P. L. Smith et al. · Genome Research · 1997 · 1.2K citations · Full text

Genetics, Molecular Genetics, Genomics +21