Michelle S. Prew

High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects

Benjamin P. Kleinstiver, Vikram Pattanayak, Michelle S. Prew et al. · Nature · 2016 · 2.6K citations · Full text

Natural Sciences, Genetic Engineering, Molecular Biology +7

Engineered CRISPR-Cas9 nucleases with altered PAM specificities

Benjamin P. Kleinstiver, Michelle S. Prew, Shengdar Q. Tsai et al. · Nature · 2015 · 1.6K citations · Full text

Engineering, Synthetic Biology, Genetic Engineering +8

Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells

Benjamin P. Kleinstiver, Shengdar Q. Tsai, Michelle S. Prew et al. · Nature Biotechnology · 2016 · 698 citations · Full text

Crispr-cas Cpf1, Gene Editing, Genome Editing +3

Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition

Benjamin P. Kleinstiver, Michelle S. Prew, Shengdar Q. Tsai et al. · Nature Biotechnology · 2015 · 616 citations · Full text

Pam Recognition, Off-target Effect, Engineering +10

Allele-Specific CRISPR-Cas9 Genome Editing of the Single-Base P23H Mutation for Rhodopsin-Associated Dominant Retinitis Pigmentosa

Pingjuan Li, Benjamin P. Kleinstiver, Mihoko Leon et al. · The CRISPR Journal · 2018 · 117 citations