Cell Reports · 2019 · 80 citations · 65 references
Life SciencesGeneticsMolecular BiologyAgingMitochondrial BiologyProtein TranslationBiological AgingLongevityMitochondrial Stress ResponsesMitochondrial TranslationTranslation RegulationTranslational RegulationAmp-activated Protein Kinase InteractionC. Elegans Developmental ModelsMitochondrial ResponseMitochondrial Rna-binding ProteinsMitochondrial Stress Response GenesMitochondrial Stress Signaling PathwaysUnfolded Protein Response
and synergistic longevity of the daf-2 rsks-1 mutant. Altogether, these results illustrate a translationally regulated non-autonomous mitochondrial stress response mechanism in the modulation of lifespan by insulin-like signaling and S6K.
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Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
PubMed · 1997 · 66.6K citations
HTSeq—a Python framework to work with high-throughput sequencing data
Simon Anders, Paul Theodor Pyl, Wolfgang Huber · Bioinformatics · 2014 · 22.7K citations · Full text