Nature Medicine · 2019 · 202 citations · 29 references
Life SciencesGeneticsMolecular GeneticsGenome EditingMedical GeneticsNeurogeneticsAllele-specific EditingCochlear DisordersCochlear NeuroscienceGenetic DisordersHearing ImpairmentHearing LossAllele-specific Gene RegulationAllele-specific Genome EditingAllele-specific TherapyMutant Allele DisruptionProgressive Hearing Loss
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Genome engineering using the CRISPR-Cas9 system
F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
Alexis C. Komor, Y. Bill Kim, Michael S. Packer et al. · Nature · 2016 · 5.4K citations · Full text
ClinVar: public archive of interpretations of clinically relevant variants
Melissa Landrum, Jennifer M. Lee, Mark J. Benson et al. · Nucleic Acids Research · 2015 · 2.9K citations · Full text
In vivo genome editing using Staphylococcus aureus Cas9
F. Ann Ran, Le Cong, Winston X. Yan et al. · Nature · 2015 · 2.7K citations · Full text
High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects
Benjamin P. Kleinstiver, Vikram Pattanayak, Michelle S. Prew et al. · Nature · 2016 · 2.7K citations · Full text