Modifications in the branched arms of a class of dual inhibitors of HIV and EV71 replication expand their antiviral spectrum

Scavenger receptor B2 is a cellular receptor for enterovirus 71

Seiya Yamayoshi, Yasuko Yamashita, Jifen Li et al. · Nature Medicine · 2009 · 510 citations

Life Sciences, Immunology, Infectious Diseases +16

Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro.

Masanori Baba, Rudi Pauwels, Jan Balzarini et al. · Proceedings of the National Academy of Sciences · 1988 · 466 citations · Full text

Medicine, Immunology, Pharmacology +7

Inhibitors of HIV-1 Attachment: The Discovery and Development of Temsavir and its Prodrug Fostemsavir

Nicholas A. Meanwell, Mark Krystal, Beata Nowicka-Sans et al. · Journal of Medicinal Chemistry · 2017 · 140 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

In vitro activity of pirodavir (R 77975), a substituted phenoxy-pyridazinamine with broad-spectrum antipicornaviral activity

Koen Andries, B. Dewindt, Jos Snoeks et al. · Antimicrobial Agents and Chemotherapy · 1992 · 126 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Pradimicin A, a Carbohydrate-Binding Nonpeptidic Lead Compound for Treatment of Infections with Viruses with Highly Glycosylated Envelopes, Such as Human Immunodeficiency Virus

Jan Balzarini, Kristel Van Laethem, Dirk Daelemans et al. · Journal of Virology · 2006 · 104 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17