Leen Delang

STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters

Robbert Boudewijns, Hendrik Jan Thibaut, Suzanne J. F. Kaptein et al. · Nature Communications · 2020 · 287 citations · Full text

Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters, whereas hydroxychloroquine lacks activity

Suzanne J. F. Kaptein, Sofie Jacobs, Lana Langendries et al. · Proceedings of the National Academy of Sciences · 2020 · 281 citations · Full text

Antiviral Compound, Emerging Infectious Diseases, Lacks Activity +14

Itraconazole Inhibits Enterovirus Replication by Targeting the Oxysterol-Binding Protein

Jeroen R. P. M. Strating, Lonneke van der Linden, Lucian Albulescu et al. · Cell Reports · 2015 · 247 citations · Full text

Viral Replication, Molecular Virology, Pathogenesis +4

Mutations in the chikungunya virus non-structural proteins cause resistance to favipiravir (T-705), a broad-spectrum antiviral

Leen Delang, Nidya Alexandra Segura Guerrero, Ali Taş et al. · Journal of Antimicrobial Chemotherapy · 2014 · 225 citations · Full text

Stable distinct core eukaryotic viromes in different mosquito species from Guadeloupe, using single mosquito viral metagenomics

Chenyan Shi, Leen Beller, Ward Deboutte et al. · Microbiome · 2019 · 153 citations · Full text