Sofie Jacobs

STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters

Robbert Boudewijns, Hendrik Jan Thibaut, Suzanne J. F. Kaptein et al. · Nature Communications · 2020 · 287 citations · Full text

Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters, whereas hydroxychloroquine lacks activity

Suzanne J. F. Kaptein, Sofie Jacobs, Lana Langendries et al. · Proceedings of the National Academy of Sciences · 2020 · 281 citations · Full text

Antiviral Compound, Emerging Infectious Diseases, Lacks Activity +14

Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains

Fabien Aubry, Sofie Jacobs, Maïlis Darmuzey et al. · Nature Communications · 2021 · 141 citations · Full text

An affinity-enhanced, broadly neutralizing heavy chain–only antibody protects against SARS-CoV-2 infection in animal models

Bert Schepens, Loes van Schie, Wim Nerinckx et al. · Science Translational Medicine · 2021 · 66 citations · Full text

Dissection of Nidogen function in Drosophila reveals tissue-specific mechanisms of basement membrane assembly

Jianli Dai, Beatriz Estrada, Sofie Jacobs et al. · PLoS Genetics · 2018 · 63 citations · Full text

Cytoskeleton, Cellular Physiology, Embryology +21