Concepedia

Engineered ethanol-driven biosynthetic system for improving production of acetyl-CoA derived drugs in Crabtree-negative yeast

Yiqi Liu, Chenxiao Bai, Qi Liu, Qin Xu, Zhilan Qian, Qiangqiang Peng, Jiahui Yu, Ming-Qiang Xu, Xiangshan Zhou, Yuanxing Zhang,

Metabolic Engineering · 2019 · 52 citations · 47 references

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Production of the antimalarial drug precursor artemisinic acid in engineered yeast

Dae‐Kyun Ro, Eric M. Paradise, Mario Ouellet et al. · Nature · 2006 · 2.8K citations

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Highly efficient Cas9-mediated transcriptional programming

Alejandro Chavez, Jonathan Scheiman, Suhani Vora et al. · Nature Methods · 2015 · 1.6K citations · Full text

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Complete biosynthesis of opioids in yeast

Stephanie Galanie, Kate Thodey, Isis J. Trenchard et al. · Science · 2015 · 999 citations · Full text

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Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin

Patrick J. Westfall, Douglas J. Pitera, Jacob R. Lenihan et al. · Proceedings of the National Academy of Sciences · 2012 · 725 citations · Full text

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Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols

José L. Avalos‬, Gerald R. Fink, Gregory Stephanopoulos · Nature Biotechnology · 2013 · 522 citations · Full text

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