Concepedia

Acetyl-coa Engineering

Acetyl-CoA Engineering is a metabolic engineering strategy that systematically modulates the biosynthesis, flux, and compartmentalization of acetyl-coenzyme A—a central metabolic node—to optimize the production of target biocompounds in microbial and plant systems.

53

Publications

4.2K

Citations

276

Authors

87

Institutions

Publications per year

2017–2026

32

Parents

Publications

53

Microbial acetyl-CoA metabolism and metabolic engineering

Anastasia Krivoruchko, Yiming Zhang, Verena Siewers et al. · Metabolic Engineering · 2014 · 338 citations

, , +14

Establishing a platform cell factory through engineering of yeast acetyl-CoA metabolism

Yun Chen, Laurent Daviet, Michel Schalk et al. · Metabolic Engineering · 2012 · 322 citations

, , +14

Constructing a synthetic pathway for acetyl-coenzyme A from one-carbon through enzyme design

Xiaoyun Lu, Yuwan Liu, Yiqun Yang et al. · Nature Communications · 2019 · 276 citations · Full text

, , +15

Dual regulation of cytoplasmic and mitochondrial acetyl-CoA utilization for improved isoprene production in Saccharomyces cerevisiae

Xiaomei Lv, Fan Wang, Pingping Zhou et al. · Nature Communications · 2016 · 258 citations · Full text

, , +15

Engineering acetyl-CoA metabolic shortcut for eco-friendly production of polyketides triacetic acid lactone in Yarrowia lipolytica

Huan Liu, Monireh Marsafari, Fang Wang et al. · Metabolic Engineering · 2019 · 150 citations

, , +16

1–5 of 53

Authors

276

  1. JN
    Jens Nielsen

    Chalmers University of Technology, Sweden

    6 publications · 1.1K citations

    6

    h-index

  2. VS
    Verena Siewers

    Chalmers University of Technology, Sweden

    5 publications · 998 citations

    5

    h-index

  3. GN
    George N. Bennett

    Rice University, United States

    4 publications · 327 citations

    4

    h-index

  4. YC
    Yun Chen

    Chalmers University of Technology, Sweden

    4 publications · 890 citations

    4

    h-index

  5. KS
    Ka‐Yiu San

    Rice University, United States

    3 publications · 277 citations

    3

    h-index

1–5 of 276

Institutions

87

  1. Chalmers University of Technology

    Gothenburg, Sweden

    6 h-index

    21 publications

    4.1K citations

  2. Rice University

    Houston, United States

    5 h-index

    16 publications

    1.3K citations

  3. Tsinghua University

    Beijing, China

    4 h-index

    19 publications

    853 citations

  4. Shandong University

    Jinan, China

    3 h-index

    19 publications

    2K citations

  5. Zhejiang University

    Hangzhou, China

    3 h-index

    15 publications

    2.5K citations

  6. Chinese Academy of Sciences

    Beijing, China

    3 h-index

    31 publications

    6.3K citations

  7. Tianjin University

    Tianjin, China

    3 h-index

    15 publications

    424 citations

  8. Beijing Institute of Technology

    Beijing, China

    2 h-index

    8 publications

    325 citations

1–8 of 87

Venues

  1. Metabolic Engineering

    12 publications · 1.5K citations

    12

    h-index

  2. ACS Synthetic Biology

    6 publications · 180 citations

    6

    h-index

  3. Biotechnology and Bioengineering

    5 publications · 330 citations

    5

    h-index

  4. Applied Microbiology and Biotechnology

    3 publications · 167 citations

    3

    h-index

  5. Journal of Agricultural and Food Chemistry

    2 publications · 86 citations

    2

    h-index

1–5