Dual regulation of cytoplasmic and mitochondrial acetyl-CoA utilization for improved isoprene production in Saccharomyces cerevisiae

Xiaomei Lv, Fan Wang, Pingping Zhou, +4

Nature Communications

Construction of lycopene-overproducing Saccharomyces cerevisiae by combining directed evolution and metabolic engineering

Wenping Xie, Xiaomei Lv, Lidan Ye, +2

Metabolic Engineering

BiosynthesisEngineeringNatural SciencesDirected EvolutionBiochemical Engineering +11

Sequential control of biosynthetic pathways for balanced utilization of metabolic intermediates in Saccharomyces cerevisiae

Wenping Xie, Lidan Ye, Xiaomei Lv, +2

Metabolic Engineering

Sequential ControlMetabolic PathwaysBiosynthesisSystems BiologyBiochemistry +11

Construction of a controllable β‐carotene biosynthetic pathway by decentralized assembly strategy in <i>Saccharomyces cerevisiae</i>

Wenping Xie, Min Liu, Xiaomei Lv, +3

Biotechnology and Bioengineering

EngineeringBiosynthesisBiochemical EngineeringMetabolic EngineeringYeast +16

Highly efficient biosynthesis of astaxanthin in Saccharomyces cerevisiae by integration and tuning of algal crtZ and bkt

Pingping Zhou, Lidan Ye, Wenping Xie, +2

Applied Microbiology and Biotechnology

BiosynthesisEngineeringBiotransformationBiochemistrySaccharomyces Cerevisiae +10

Combining Gal4p-mediated expression enhancement and directed evolution of isoprene synthase to improve isoprene production in Saccharomyces cerevisiae

Fan Wang, Xiaomei Lv, Wenping Xie, +7

Metabolic Engineering

BiosynthesisEngineeringBiochemistryNatural SciencesBiotechnology +10

Significantly enhanced production of isoprene by ordered coexpression of genes dxs, dxr, and idi in Escherichia coli

Xiaomei Lv, Haoming Xu, Hongwei Yu

Applied Microbiology and Biotechnology

BiosynthesisEngineeringGenes DxsOrdered CoexpressionBacteriology +10

Enhanced isoprene biosynthesis in Saccharomyces cerevisiae by engineering of the native acetyl-CoA and mevalonic acid pathways with a push-pull-restrain strategy

Xiaomei Lv, Wenping Xie, Wenqiang Lu, +4

Journal of Biotechnology

BiosynthesisEnhanced Isoprene BiosynthesisEngineeringBiochemistryNatural Sciences +13

Combinatorial pathway optimization in <i>Escherichia coli</i> by directed co‐evolution of rate‐limiting enzymes and modular pathway engineering

Xiaomei Lv, Jiali Gu, Fan Wang, +4

Biotechnology and Bioengineering

EngineeringMetabolic NetworksModular Pathway EngineeringMicrobial EvolutionMetabolic Model +20

Identification and elimination of metabolic bottlenecks in the quinone modification pathway for enhanced coenzyme Q10 production in Rhodobacter sphaeroides

Wenqiang Lu, Lidan Ye, Xiaomei Lv, +6

Metabolic Engineering

BiosynthesisEngineeringBiochemistryQuinone Modification PathwayBiotechnology +7