Xiaoyun Lu

Constructing a synthetic pathway for acetyl-coenzyme A from one-carbon through enzyme design

Xiaoyun Lu, Yuwan Liu, Yiqun Yang et al. · Nature Communications · 2019 · 276 citations · Full text

Engineering, Biochemistry, Biotechnology +15

Identification of GZD824 as an Orally Bioavailable Inhibitor That Targets Phosphorylated and Nonphosphorylated Breakpoint Cluster Region–Abelson (Bcr-Abl) Kinase and Overcomes Clinically Acquired Mutation-Induced Resistance against Imatinib

Xiaomei Ren, Xiaofen Pan, Zhang Zhang et al. · Journal of Medicinal Chemistry · 2013 · 181 citations · Full text

Medicine, Oncology, Pharmacology +13

Discovery and Optimization of 3-(2-(Pyrazolo[1,5-<i>a</i>]pyrimidin-6-yl)ethynyl)benzamides as Novel Selective and Orally Bioavailable Discoidin Domain Receptor 1 (DDR1) Inhibitors

Mingshan Gao, Lei Duan, Jinfeng Luo et al. · Journal of Medicinal Chemistry · 2013 · 157 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9

Design, Synthesis, and in Vitro Biological Evaluation of 1<i>H</i>-1,2,3-Triazole-4-carboxamide Derivatives as New Anti-influenza A Agents Targeting Virus Nucleoprotein

Huimin Cheng, Junting Wan, Meng‐I Lin et al. · Journal of Medicinal Chemistry · 2012 · 144 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Synthesis and evaluation of anti-tubercular and antibacterial activities of new 4-(2,6-dichlorobenzyloxy)phenyl thiazole, oxazole and imidazole derivatives. Part 2

Xiaoyun Lu, Xiaobo Liu, Baojie Wan et al. · European Journal of Medicinal Chemistry · 2012 · 131 citations

Pharmacy, Chemistry, Medicinal Chemistry +12