Concepedia

Genetic Deficiency and Biochemical Inhibition of ITK Affect Human Th17, Treg, and Innate Lymphoid Cells

Ahmet Eken, Murat Cansever, Ido Somekh, Yoko Mizoguchi, Natalia Ziętara, Fatma Zehra Okuş, Şerife Erdem, Halit Canatan, Şefika Akyol, Alper Özcan,

Journal of Clinical Immunology · 2019 · 43 citations · 34 references

DOI

Concepts

References

34

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

Daniel R. Neill, See Heng Wong, Agustin Bellosi et al. · Nature · 2010 · 2K citations · Full text

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Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes

Jason A. Dubovsky, Kyle A. Beckwith, Gayathri Natarajan et al. · Blood · 2013 · 796 citations

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Requirement for Tec Kinases Rlk and Itk in T Cell Receptor Signaling and Immunity

Edward M. Schaeffer, Jayanta Debnath, George Yap et al. · Science · 1999 · 401 citations

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Cutting Edge: IL-23 Receptor GFP Reporter Mice Reveal Distinct Populations of IL-17-Producing Cells

Amit Awasthi, Lorena Riol‐Blanco, Anneli Jäger et al. · The Journal of Immunology · 2009 · 363 citations · Full text

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Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk

Xiang Liao, Dan R. Littman · Immunity · 1995 · 313 citations

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