Akt and STAT5 mediate naïve human CD4+ T-cell early metabolic response to TCR stimulation

The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation

Ruoning Wang, Christopher P. Dillon, Lewis Z. Shi et al. · Immunity · 2011 · 2K citations · Full text

Transcriptional Regulation, T Lymphocyte Activation, Lymphocyte Development +12

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

Christian M. Metallo, Paulo A. Gameiro, Eric L. Bell et al. · Nature · 2011 · 1.7K citations · Full text

Biochemistry, Redox Regulator, Hypoxia (Medicine) +5

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses

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Energy Metabolism, Signal Transduction, Biochemistry +12

The Glucose Transporter Glut1 Is Selectively Essential for CD4 T Cell Activation and Effector Function

Andrew N. Macintyre, Valerie A. Gerriets, Amanda Nichols et al. · Cell Metabolism · 2014 · 1.1K citations · Full text

Signal Transduction, Effector Function, Diabetes +9

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation

Bart Everts, Eyal Amiel, Stanley Ching‐Cheng Huang et al. · Nature Immunology · 2014 · 1K citations · Full text

Signal Transduction, Signaling Pathway, Receptor Tyrosine Kinase +9