Ping‐Chih Ho

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses

Ping‐Chih Ho, Jessica Bihuniak, Andrew N. Macintyre et al. · Cell · 2015 · 1.4K citations · Full text

Energy Metabolism, Signal Transduction, Biochemistry +12

A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade

Daniela S. Thommen, Viktor H. Koelzer, Petra Herzig et al. · Nature Medicine · 2018 · 1.1K citations · Full text

Cancer Immunosurveillance, Non-small-cell Lung Cancer, Pd-1 Blockade +8

α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming

Haiping Wang, Xiaoyun Li, Tung Chao et al. · Nature Immunology · 2017 · 1.1K citations · Full text

Epigenetic Reprogramming, Metabolic Regulation, Metabolism +2

Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors

Shihao Xu, Omkar Chaudhary, Patricia Rodríguez-Morales et al. · Immunity · 2021 · 673 citations · Full text

Cancer Immunosurveillance, Lipid Peroxidation, Immunology +9

CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors

Haiping Wang, Fabien Franco, Yao-Chen Tsui et al. · Nature Immunology · 2020 · 609 citations · Full text

Cancer Immunosurveillance, Medicine, T-regulatory Cell +10