α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming

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Macrophage Biology, Inflammation, Cytokine +9

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Succinate is an inflammatory signal that induces IL-1β through HIF-1α

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Inflammation, Cytokine, Inflammatory Disease +10

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

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Genetic Engineering, Genome Engineering, Gene Editing +4