Stefan Christen

α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming

Haiping Wang, Xiaoyun Li, Tung Chao et al. · Nature Immunology · 2017 · 1.1K citations · Full text

Epigenetic Reprogramming, Metabolic Regulation, Metabolism +2

Fatty acid carbon is essential for dNTP synthesis in endothelial cells

Sandra Schoors, Ulrike Brüning, Rindert Missiaen et al. · Nature · 2015 · 626 citations · Full text

Angiogenesis, Fatty Acid Carbon, Biochemistry +11

Quantitative Phosphoproteomics Reveal mTORC1 Activates de Novo Pyrimidine Synthesis

Aaron M. Robitaille, Stefan Christen, Mitsugu Shimobayashi et al. · Science · 2013 · 506 citations

Signal Transduction, Signaling Pathway, Biochemistry +14

Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity

Kim Vriens, Stefan Christen, Sweta Parik et al. · Nature · 2019 · 468 citations · Full text

Lineage Plasticity, Lipid Synthesis, Omega-3 Fatty Acid +8

Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells

Ilaria Elia, Dorien Broekaert, Stefan Christen et al. · Nature Communications · 2017 · 413 citations · Full text