Concepedia

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

Christian M. Metallo, Paulo A. Gameiro, Eric L. Bell, Katherine Mattaini, Juanjuan Yang, Karsten Hiller, Christopher M. Jewell, Zachary Johnson, Darrell J. Irvine, Leonard Guarente,

Nature · 2011 · 1.8K citations · 38 references

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38

Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex

Dos D. Sarbassov, David A. Guertin, Siraj M. Ali et al. · Science · 2005 · 6.2K citations

, , +17

Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O <sub>2</sub> -Regulated Prolyl Hydroxylation

Panu Jaakkola, David R. Mole, Ya‐Min Tian et al. · Science · 2001 · 5.5K citations

, , +17

HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O <sub>2</sub> Sensing

Mircea Ivan, Keiichi Kondo, Haifeng Yang et al. · Science · 2001 · 4.7K citations · Full text

, , +16

HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia

Jung‐whan Kim, Irina Tchernyshyov, Gregg L. Semenza et al. · Cell Metabolism · 2006 · 3.9K citations · Full text

, , +17

T cell receptor antagonist peptides induce positive selection

Kristin A. Hogquist, Stephen C. Jameson, William R. Heath et al. · Cell · 1994 · 2.9K citations

, , +13