Concepedia
Statistics
Publications
46
Citations
7.2K
H-Index
32
Active since
2004
Affiliations
Trinity College Dublin(Current)
University of Dundee
St. Vincent's University Hospital
Trinity College
Swansea University
David K. Finlay is an author at Trinity College Dublin specializing in medicine, cell biology, and cell signaling.
Top concepts
MedicineCell BiologyImmunologyCell SignalingSignal TransductionImmunotherapyCell PhysiologyImmune RegulationMetabolic RegulationCell Death
Publications per year
2004–2025
T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR
Stephan Sauer, Ludovica Bruno, Arnulf Hertweck et al. · Proceedings of the National Academy of Sciences · 2008 · 821 citations · Full text
Immune Pathology, T-regulatory Cell, Immunology +22
TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway
Sébastien Viel, Antoine Marçais, Fernando Guimarães et al. · Science Signaling · 2016 · 611 citations
Metabolic reprogramming of natural killer cells in obesity limits antitumor responses
Xavier Michelet, Lydia Dyck, Andrew E. Hogan et al. · Nature Immunology · 2018 · 584 citations
Energy Homeostasis, Natural Killer Cells, Metabolic Reprogramming +12
PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells
David K. Finlay, Ella Rosenzweig, Linda V. Sinclair et al. · The Journal of Experimental Medicine · 2012 · 571 citations · Full text
mTORC1-Dependent Metabolic Reprogramming Is a Prerequisite for NK Cell Effector Function
Raymond P. Donnelly, Róisín M. Loftus, Sinéad E. Keating et al. · The Journal of Immunology · 2014 · 445 citations
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