Róisín M. Loftus

TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway

Sébastien Viel, Antoine Marçais, Fernando Guimarães et al. · Science Signaling · 2016 · 611 citations

Metabolic reprogramming of natural killer cells in obesity limits antitumor responses

Xavier Michelet, Lydia Dyck, Andrew E. Hogan et al. · Nature Immunology · 2018 · 584 citations

Energy Homeostasis, Natural Killer Cells, Metabolic Reprogramming +12

mTORC1-Dependent Metabolic Reprogramming Is a Prerequisite for NK Cell Effector Function

Raymond P. Donnelly, Róisín M. Loftus, Sinéad E. Keating et al. · The Journal of Immunology · 2014 · 445 citations

Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice

Róisín M. Loftus, Nidhi Kedia-Mehta, Katie O’Brien et al. · Nature Communications · 2018 · 358 citations · Full text

Srebp-controlled glucose metabolism is essential for NK cell functional responses

Katie O’Brien, Raymond P. Donnelly, Lydia Dyck et al. · Nature Immunology · 2017 · 342 citations · Full text

Energy Homeostasis, Signal Transduction, Diabetes +11