Concepedia

Srebp-controlled glucose metabolism is essential for NK cell functional responses

Katie O’Brien, Raymond P. Donnelly, Lydia Dyck, Vanessa Zaiatz-Bittencourt, Róisín M. Loftus, Paul V. Heinrich, Peter J. Oefner, Lydia Lynch, Clair M. Gardiner, Katja Dettmer,

Nature Immunology · 2017 · 363 citations · 45 references

DOIFull text

Open access

Concepts

References

45

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

Jay D. Horton, Joseph L. Goldstein, Michael S. Brown · Journal of Clinical Investigation · 2002 · 4K citations · Full text

, , +17

mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity

Shih‐Chin Cheng, Jessica Quintin, Robert A. Cramer et al. · Science · 2014 · 2.1K citations

, , +17

Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1

Katrin Düvel, Jessica L. Yecies, Suchithra Menon et al. · Molecular Cell · 2010 · 2K citations · Full text

, , +13

Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages

Stanley Ching‐Cheng Huang, Bart Everts, Yulia Ivanova et al. · Nature Immunology · 2014 · 1.2K citations · Full text

, , +12

Global burden of cancer attributable to high body-mass index in 2012: a population-based study

Melina Arnold, Nirmala Pandeya, Graham Byrnes et al. · The Lancet Oncology · 2014 · 993 citations · Full text

, , +17