Lydia Lynch

Metabolic reprogramming of natural killer cells in obesity limits antitumor responses

Xavier Michelet, Lydia Dyck, Andrew E. Hogan et al. · Nature Immunology · 2018 · 584 citations

Energy Homeostasis, Natural Killer Cells, Metabolic Reprogramming +12

Adipose Tissue Invariant NKT Cells Protect against Diet-Induced Obesity and Metabolic Disorder through Regulatory Cytokine Production

Lydia Lynch, Michael Nowak, Bindu Varghese et al. · Immunity · 2012 · 491 citations · Full text

Obesity, Inflammation, Metabolic Syndrome +15

Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer

Di Wu, Di Hu, Hao Chen et al. · Nature · 2018 · 465 citations

Tumor Biology, Glucose-regulated Phosphorylation, Signal Transduction +12

Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of Treg cells and macrophages in adipose tissue

Lydia Lynch, Xavier Michelet, Sai Zhang et al. · Nature Immunology · 2014 · 365 citations · Full text

Srebp-controlled glucose metabolism is essential for NK cell functional responses

Katie O’Brien, Raymond P. Donnelly, Lydia Dyck et al. · Nature Immunology · 2017 · 342 citations · Full text

Energy Homeostasis, Signal Transduction, Diabetes +11