Lydia Lynch

Metabolic reprogramming of natural killer cells in obesity limits antitumor responses

Xavier Michelet, Lydia Dyck, Andrew E. Hogan et al. · Nature Immunology · 2018 · 610 citations

Life Sciences, Cancer Biology, Immunology +16

Adipose Tissue Invariant NKT Cells Protect against Diet-Induced Obesity and Metabolic Disorder through Regulatory Cytokine Production

Lydia Lynch, Michael Nowak, Bindu Varghese et al. · Immunity · 2012 · 496 citations · Full text

Life Sciences, Immunology, Physiology +16

Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer

Di Wu, Di Hu, Hao Chen et al. · Nature · 2018 · 480 citations

Life Sciences, Cancer Biology, Cell Biology +12

Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of Treg cells and macrophages in adipose tissue

Lydia Lynch, Xavier Michelet, Sai Zhang et al. · Nature Immunology · 2014 · 368 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +13

Srebp-controlled glucose metabolism is essential for NK cell functional responses

Katie O’Brien, Raymond P. Donnelly, Lydia Dyck et al. · Nature Immunology · 2017 · 363 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12