Concepedia

Development of a gene-editing approach to restore vision loss in Leber congenital amaurosis type 10

Morgan L. Maeder, Michael Stefanidakis, Christopher J. Wilson, Reshica Baral, Luis Barrera, George S. Bounoutas, David Bumcrot, Hoson Chao, Dawn Ciulla, Jennifer A. DaSilva,

Nature Medicine · 2019 · 706 citations · 29 references

DOI

Concepts

References

29

The Sequence Alignment/Map format and SAMtools

Heng Li, Alec Wysoker, Tim Fennell et al. · Bioinformatics · 2009 · 67.5K citations · Full text

, , +17

Fast gapped-read alignment with Bowtie 2

Ben Langmead, Steven L. Salzberg · Nature Methods · 2012 · 61.1K citations

, , +11

Cutadapt removes adapter sequences from high-throughput sequencing reads

Marcel Martin · EMBnet journal · 2011 · 35.8K citations · Full text

, , +8

The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability

F. Niesen, H. Berglund, Masoud Vedadi · Nature Protocols · 2007 · 2.4K citations

, , +14

Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

Sangsu Bae, Jeongbin Park, Jin‐Soo Kim · Bioinformatics · 2014 · 2.4K citations · Full text

, , +13