David Bumcrot

RNAi-mediated gene silencing in non-human primates

Tracy Zimmermann, Amy C. H. Lee, Akin Akinc et al. · Nature · 2006 · 1.3K citations

Genetics, Rnai-mediated Gene, Antisense Therapy +1

First-in-Humans Trial of an RNA Interference Therapeutic Targeting VEGF and KSP in Cancer Patients with Liver Involvement

Josep Tabernero, Geoffrey I. Shapiro, Patricia LoRusso et al. · Cancer Discovery · 2013 · 691 citations

Development of a gene-editing approach to restore vision loss in Leber congenital amaurosis type 10

Morgan L. Maeder, Michael Stefanidakis, Christopher J. Wilson et al. · Nature Medicine · 2019 · 674 citations

Ocular Disease, Developmental Biology, Retina +9

Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite.

Andrea Münsterberg, Jan Kitajewski, David Bumcrot et al. · Genes & Development · 1995 · 507 citations · Full text

Genetics, Cytoskeleton, Cellular Physiology +19

Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants

David Bumcrot, Ritsuko Takada, Andrew P. McMahon · Nature · 1995 · 496 citations

Biology, Cell Lineage, Developmental Biology +9