Concepedia

Diaryl hydroxylamines as pan or dual inhibitors of indoleamine 2,3-dioxygenase-1, indoleamine 2,3-dioxygenase-2 and tryptophan dioxygenase

Maria Winters, James B. DuHadaway, Khoa Pham, Ariel Lewis-Ballester, Shorouk Badir, Jenny Wai, Eesha Sheikh, Syun‐Ru Yeh, George C. Prendergast, Alexander J. Muller,

European Journal of Medicinal Chemistry · 2018 · 49 citations · 36 references

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36

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

Christiane A. Opitz, Ulrike Litzenburger, Felix Sahm et al. · Nature · 2011 · 1.9K citations · Full text

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Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy

Alexander J. Muller, James B. DuHadaway, Preston S. Donover et al. · Nature Medicine · 2005 · 1.1K citations

, , +16

Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4

Rikke Holmgaard, Dmitriy Zamarin, David H. Munn et al. · The Journal of Experimental Medicine · 2013 · 636 citations · Full text

, , +17

Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase

Luc Pilotte, Pierre Larrieu, Vincent Stroobant et al. · Proceedings of the National Academy of Sciences · 2012 · 570 citations · Full text

, , +14

Crystal structure of human indoleamine 2,3-dioxygenase: Catalytic mechanism of O <sub>2</sub> incorporation by a heme-containing dioxygenase

Hiroshi Sugimoto, Shun-ichiro Oda, Takashi Ôtsuki et al. · Proceedings of the National Academy of Sciences · 2006 · 426 citations · Full text

, , +17