Concepedia

Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia

Daniel A. Pollyea, Brett M. Stevens, Courtney L. Jones, Amanda Winters, Shanshan Pei, Mohammad Minhajuddin, Angelo D’Alessandro, Rachel Culp‐Hill, Kent Riemondy, Austin E. Gillen,

Nature Medicine · 2018 · 797 citations · 35 references

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35

On the Origin of Cancer Cells

Otto Warbürg · Science · 1956 · 13.3K citations

, , +12

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

Dominique Bonnet, John E. Dick · Nature Medicine · 1997 · 6.9K citations

, , +14

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

Tsvee Lapidot, Christian Sirard, Josef Vormoor et al. · Nature · 1994 · 4.7K citations

, , +14

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

Andrew J. Souers, Joel D. Leverson, Erwin R. Boghaert et al. · Nature Medicine · 2013 · 3K citations

, , +10

Revised Recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia

Bruce D. Cheson, John M. Bennett, Thomas Büchner et al. · Journal of Clinical Oncology · 2003 · 2.7K citations

, , +17