Angelo D’Alessandro

Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia

Daniel A. Pollyea, Brett M. Stevens, Courtney L. Jones et al. · Nature Medicine · 2018 · 768 citations · Full text

Hematological Malignancy, Medicine, Acute Myeloid Leukemia +9

COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status

Tiffany Thomas, Davide Stefanoni, Julie A. Reisz et al. · JCI Insight · 2020 · 591 citations · Full text

Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells

Courtney L. Jones, Brett M. Stevens, Angelo D’Alessandro et al. · Cancer Cell · 2018 · 539 citations · Full text

Hematological Malignancy, Biochemistry, Medicine +5

OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation

Carlo Marchetti, Benjamin J. Swartzwelter, Fabia Gamboni et al. · Proceedings of the National Academy of Sciences · 2018 · 520 citations · Full text

Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia

Shanshan Pei, Daniel A. Pollyea, Annika Gustafson et al. · Cancer Discovery · 2020 · 518 citations

Mixed-phenotype Acute Leukemia, Immunology, Pharmacotherapy +19