Concepedia

Complete Substrate Inhibition of Cytochrome P450 2C8 by AZD9496, an Oral Selective Estrogen Receptor Degrader

Tashinga E. Bapiro, Andy Sykes, Scott Martin, Michael Davies, James Yates, Matthias Hoch, Helen Rollison, Barry Jones

Drug Metabolism and Disposition · 2018 · 17 citations · 22 references

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Concepts

References

22

Crystal Structures of Human Cytochrome P450 3A4 Bound to Metyrapone and Progesterone

Pamela A. Williams, José Cosme, Dijana Matak‐Vinković et al. · Science · 2004 · 806 citations

, , +15

The prediction of human pharmacokinetic parameters from preclinical and in vitro metabolism data

Kaoxiang Sun · Chinese New Drugs Journal · 2005 · 764 citations

, , +14

The prediction of human pharmacokinetic parameters from preclinical and in vitro metabolism data.

R. Scott Obach, James G. Baxter, Theodore E. Liston et al. · PubMed · 1997 · 638 citations

, , +14

The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data

R. Scott Obach, James G. Baxter, Theodore E. Liston et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 591 citations

, , +14

Evaluation of Atypical Cytochrome P450 Kinetics with Two-Substrate Models:  Evidence That Multiple Substrates Can Simultaneously Bind to Cytochrome P450 Active Sites

Ken Korzekwa, N. Krishnamachary, Magang Shou et al. · Biochemistry · 1998 · 519 citations

, , +17