Andy Sykes

Machine Learning Models for Human <i>In Vivo</i> Pharmacokinetic Parameters with In-House Validation

Filip Miljković, Anton Martinsson, Olga Obrezanova et al. · Molecular Pharmaceutics · 2021 · 91 citations

Pharmacy, Pharmacokinetics, Pharmacology +12

Brain exposure of the ATM inhibitor AZD1390 in humans—a positron emission tomography study

Aurelija Jučaitė, Per Stenkrona, Zsolt Cselényi et al. · Neuro-Oncology · 2020 · 66 citations · Full text

Medicine, Nuclear Medicine, Pharmacology +16

Identification of a novel GPR81-selective agonist that suppresses lipolysis in mice without cutaneous flushing

Taku Sakurai, Richard Davenport, Stuart Stafford et al. · European Journal of Pharmacology · 2014 · 54 citations

Life Sciences, Medicinal Chemistry, Pharmacology +8

A phase I dose escalation and expansion study of the next generation oral SERD AZD9833 in women with ER-positive, HER2-negative advanced breast cancer.

Erika Hamilton, Mafalda Oliveira, Udai Banerji et al. · Journal of Clinical Oncology · 2020 · 42 citations · Full text

Medicine, Oncology, Pharmacology +17

An Exploratory Study of Daprodustat in Erythropoietin-Hyporesponsive Subjects

Borut Čižman, Andy Sykes, Gitanjali Paul et al. · Kidney International Reports · 2018 · 36 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17