Concepedia

Human colorectal cancer initiation is bidirectional, and cell growth, metabolic genes and transporter genes are early drivers of tumorigenesis

Hong Yi, Soo Chin Liew, Lai Fun Thean, Choong Leong Tang, Peh Yean Cheah

Cancer Letters · 2018 · 19 citations · 26 references

DOI

Concepts

References

26

Identification of stem cells in small intestine and colon by marker gene Lgr5

Nick Barker, Johan H. van Es, Jeroen Kuipers et al. · Nature · 2007 · 5.7K citations

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Crypt stem cells as the cells-of-origin of intestinal cancer

Nick Barker, Rachel A. Ridgway, Johan H. van Es et al. · Nature · 2008 · 2.2K citations

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The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells

Marc van de Wetering, Elena Sancho, Cornelis L. Verweij et al. · Cell · 2002 · 2K citations · Full text

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Efficient tumour formation by single human melanoma cells

Elsa Quintana, Mark Shackleton, Michael S. Sabel et al. · Nature · 2008 · 1.8K citations · Full text

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Cancer Stem Cells: An Old Idea—A Paradigm Shift

Max S. Wicha, Suling Liu, Gabriela Dontu · Cancer Research · 2006 · 1.4K citations

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