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New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting

Riccardo Rondanin, Giacomo Lettini, Paola Oliva, Riccardo Baruchello, Cristiana Costantini, Claudio Trapella, Daniele Simoni, Tatiana Bernardi, Lorenza Sisinni, Michele Pietrafesa,

Bioorganic & Medicinal Chemistry Letters · 2018 · 20 citations · 21 references

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21

NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis

Suzanne A. Eccles, Andy Massey, Florence I. Raynaud et al. · Cancer Research · 2008 · 478 citations · Full text

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Regulation of Tumor Cell Mitochondrial Homeostasis by an Organelle-Specific Hsp90 Chaperone Network

Byoung Heon Kang, Janet Plescia, Takehiko Dohi et al. · Cell · 2007 · 446 citations · Full text

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Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90

Byoung Heon Kang, Janet Plescia, Ho Young Song et al. · Journal of Clinical Investigation · 2009 · 242 citations · Full text

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Tumor necrosis factor-associated protein 1 (TRAP-1) protects cells from oxidative stress and apoptosis

Nicola Montesano Gesualdi, Giuseppa Chirico, Giuseppe Pirozzi et al. · Stress · 2007 · 173 citations · Full text

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Cytoprotective Mitochondrial Chaperone TRAP-1 As a Novel Molecular Target in Localized and Metastatic Prostate Cancer

Irwin Leav, Janet Plescia, Hira Lal Goel et al. · American Journal Of Pathology · 2009 · 128 citations · Full text

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