Synthesis and Biological Evaluation of Resveratrol and Analogues as Apoptosis-Inducing Agents

Marinella Roberti, Daniela Pizzirani, Daniele Simoni, +6

Journal of Medicinal Chemistry

Chemoprevention StrategyApoptosisCell DeathCancer InitiationTriphenolic Stilbene +14

Heterocyclic and Phenyl Double-Bond-Locked Combretastatin Analogues Possessing Potent Apoptosis-Inducing Activity in HL60 and in MDR Cell Lines

Daniele Simoni, Giuseppina Grisolia, Giuseppe Giannini, +17

Journal of Medicinal Chemistry

1,5,7-Triazabicyclo[4.4.0]dec-1-ene (TBD), 7-methyl-TBD (MTBD) and the polymer-supported TBD (P-TBD): three efficient catalysts for the nitroaldol (Henry) reaction and for the addition of dialkyl phosphites to unsaturated systems

Daniele Simoni, Riccardo Rondanin, Massimo Morini, +2

Tetrahedron Letters

Inorganic ChemistryEngineeringOrganic ChemistryOrganometallic CatalysisCatalysis +7

Novel Combretastatin Analogues Endowed with Antitumor Activity

Daniele Simoni, Romeo Romagnoli, Riccardo Baruchello, +12

Journal of Medicinal Chemistry

Tetramethylguanidine (TMG)-catalyzed addition of dialkyl phosphites to α,β-unsaturated carbonyl compounds, alkenenitriles, aldehydes, ketones and imines

Daniele Simoni, Francesco Paolo Invidiata, Monica Manferdini, +4

Tetrahedron Letters

Engineeringβ-Unsaturated Carbonyl CompoundsOrganic ChemistryChemistryDialkyl Phosphites +3

Strong Bicyclic Guanidine Base-Promoted Wittig and Horner−Wadsworth−Emmons Reactions

Daniele Simoni, Marcello Rossi, Riccardo Rondanin, +5

Organic Letters

Heterocycle-Containing Retinoids. Discovery of a Novel Isoxazole Arotinoid Possessing Potent Apoptotic Activity in Multidrug and Drug-Induced Apoptosis-Resistant Cells

Daniele Simoni, Marinella Roberti, Francesco Paolo Invidiata, +16

Journal of Medicinal Chemistry

Antitumor effects of curcumin and structurally β-diketone modified analogs on multidrug resistant cancer cells

Daniele Simoni, Michele Rizzi, Riccardo Rondanin, +9

Bioorganic & Medicinal Chemistry Letters

Tumor BiologyMedicinal ChemistryOncologyMedicineβ-Diketone Modified Analogs +8

Design, Synthesis, and Biological Evaluation of Novel Aminobisphosphonates Possessing an in Vivo Antitumor Activity Through a γδ-T Lymphocytes-Mediated Activation Mechanism

Daniele Simoni, Nicola Gebbia, Francesco Paolo Invidiata, +15

Journal of Medicinal Chemistry

Antitumor ActivityImmunologyPharmacotherapyImmunotherapyPharmaceutical Chemistry +14

Novel A-Ring and B-Ring Modified Combretastatin A-4 (CA-4) Analogues Endowed with Interesting Cytotoxic Activity

Daniele Simoni, Romeo Romagnoli, Riccardo Baruchello, +10

Journal of Medicinal Chemistry

New HeterocombretastatinsMedicinal ChemistryAnti-cancer AgentRadiation OncologyCancer Research +14