Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2-<i>d</i>]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors

Romeo Romagnoli, Filippo Prencipe, Paola Oliva, +13

Journal of Medicinal Chemistry

Cinnamic acid derivatives linked to arylpiperazines as novel potent inhibitors of tyrosinase activity and melanin synthesis

Romeo Romagnoli, Paola Oliva, Filippo Prencipe, +9

European Journal of Medicinal Chemistry

Medicinal ChemistryPharmaceutical ChemistryTyrosinase ActivityBiochemistryMedicine +8

Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3′,4′,5′-Trimethoxyphenyl)-2-Aryl-1H-Imidazole

Romeo Romagnoli, Pier Giovanni Baraldi, Filippo Prencipe, +11

Scientific Reports

Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors

Paola Oliva, Romeo Romagnoli, Stefano Manfredini, +10

European Journal of Medicinal Chemistry

Medicinal ChemistryBiochemistryMedicineNatural SciencesVivo Biological Evaluation +4

Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents

Romeo Romagnoli, Pier Giovanni Baraldi, Filippo Prencipe, +7

European Journal of Medicinal Chemistry

Medicinal ChemistryDerivative (Chemistry)Novel Anticancer AgentsEngineeringMedicine +8

Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors

Romeo Romagnoli, Paola Oliva, María Kimatrai Salvador, +11

European Journal of Medicinal Chemistry

Medicinal ChemistryMedicineDrug DiscoveryRational Drug DesignPharmacotherapy +6

Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents

Romeo Romagnoli, Pier Giovanni Baraldi, Filippo Prencipe, +12

Scientific Reports

3-Aryl/Heteroaryl-5-amino-1-(3′,4′,5′-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization

Romeo Romagnoli, Filippo Prencipe, Paola Oliva, +7

Bioorganic Chemistry

Antimicrotubule AgentsMedicinal ChemistryAntiproliferative ActivityMedicineDrug Discovery +5

2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition

Romeo Romagnoli, María Kimatrai Salvador, Santiago Schiaffino Ortega, +11

European Journal of Medicinal Chemistry

Antimicrotubule AgentsMedicinal Chemistry2-Alkoxycarbonyl-3-arylamino-5-substituted ThiophenesBiochemistryMedicine +6

New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting

Riccardo Rondanin, Giacomo Lettini, Paola Oliva, +14

Bioorganic & Medicinal Chemistry Letters

MitophagyBiochemistryMitochondrial FunctionMedicineNatural Sciences +7