Pigment Epithelium-Derived Factor Plays a Role in Alzheimer's Disease by Negatively Regulating Aβ42

Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy

Maj-Linda B. Selenica, Milene L. Brownlow, Jeffy P. Jimenez et al. · Neurodegenerative Diseases · 2012 · 10.4K citations · Full text

Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

Donalyn Scheuner, Christopher B. Eckman, M. Jensen et al. · Nature Medicine · 1996 · 2.6K citations

Molecular Biology, Synaptic Signaling, Social Sciences +16

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

Bart De Strooper, Paul Säftig, Katleen Craessaerts et al. · Nature · 1998 · 1.8K citations

Neurodegenerative Diseases, Alzheimer's Disease, Molecular Biology +9

Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset.

Ron Brookmeyer, Steven G. Gray, Claudia H. Kawas · American Journal of Public Health · 1998 · 1.8K citations · Full text

Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease – is this type 3 diabetes?

Eric van Steen, Benjamin M. Terry, Enrique J. Rivera et al. · Journal of Alzheimer s Disease · 2005 · 1.7K citations