Concepedia

B-cell tumor development in Tet2-deficient mice

Enguerran Mouly, Hussein Ghamlouch, Véronique Della-Valle, Laurianne Scourzic, Cyril Quivoron, Damien Roos‐Weil, Patrycja Pawlikowska, Véronique Saada, M’Boyba Diop, Cécile K. Lopez,

Blood Advances · 2018 · 49 citations · 42 references

DOIFull text

Open access

Concepts

Abstract

deficiency predisposes to mature B-cell malignancies, which development might be attributed in part to AID-mediated accumulating mutations and BCR-mediated signaling.

References

42

Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme

Masamichi Muramatsu, Kazuo Kinoshita, Sidonia Fagarasan et al. · Cell · 2000 · 3.4K citations

, , +14

Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes

David P. Steensma, Rafael Bejar, Siddhartha Jaiswal et al. · Blood · 2015 · 1.9K citations · Full text

, , +16

Mutation in <i>TET2</i> in Myeloid Cancers

François Delhommeau, Sabrina Dupont, Véronique Della Valle et al. · New England Journal of Medicine · 2009 · 1.7K citations · Full text

, , +13

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow.

Richard R. Hardy, Condie E. Carmack, Susan A. Shinton et al. · The Journal of Experimental Medicine · 1991 · 1.6K citations · Full text

, , +17

The Origin and Evolution of Mutations in Acute Myeloid Leukemia

John S. Welch, Timothy J. Ley, Daniel C. Link et al. · Cell · 2012 · 1.6K citations · Full text

, , +12