Publication | Open Access
Serum caffeine and metabolites are reliable biomarkers of early Parkinson disease
103
Citations
31
References
2018
Year
This study provides Class III evidence that decreased serum levels of caffeine and its metabolites identify patients with PD.
| Year | Citations | |
|---|---|---|
2009 | 6.6K | |
2014 | 1.9K | |
2013 | 1.8K | |
2015 | 1.3K | |
2001 | 677 | |
Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines. Marguerite A. Butler, M. Iwasaki, F. Peter Guengerich, Proceedings of the National Academy of Sciences Metabolomic ProfilingPharmacotherapyCytochrome P-450paToxicological MechanismCarbonyl Metabolism | 1989 | 638 |
2001 | 509 | |
2001 | 442 | |
2011 | 417 | |
1999 | 354 |
Page 1
Page 1