Inactivation of Human Manganese-superoxide Dismutase by Peroxynitrite Is Caused by Exclusive Nitration of Tyrosine 34 to 3-Nitrotyrosine

Fumiyuki Yamakura, Hikari Taka, Tsutomu Fujimura, +1

Journal of Biological Chemistry

Liver autophagy contributes to the maintenance of blood glucose and amino acid levels

Junji Ezaki, Naomi Matsumoto, Mitsue Takeda‐Ezaki, +15

Autophagy

MitophagyPathologyFatty Liver DiseaseInsulin SignalingOxidative Stress +26

Altered Quinone Biosynthesis in the Long-lived clk-1Mutants of Caenorhabditis elegans

Hiroko Miyadera, Hisako Amino, Akira Hiraishi, +7

Journal of Biological Chemistry

BiologyReductive StressBiosynthesisMitochondrial BiogenesisMitochondrial Function +13

A metabolic profile of polyamines in parkinson disease: A promising biomarker

Shinji Saiki, Yukiko Sasazawa, Motoki Fujimaki, +17

Annals of Neurology

Hypoxia followed by reoxygenation induces secretion of cyclophilin A from cultured rat cardiac myocytes

Yoshinori Seko, Tsutomu Fujimura, Hikari Taka, +3

Biochemical and Biophysical Research Communications

InflammationCardiac MuscleMolecular PhysiologyRedox RegulatorReoxygenation Induces Secretion +9

Serum caffeine and metabolites are reliable biomarkers of early Parkinson disease

Motoki Fujimaki, Shinji Saiki, Yuanzhe Li, +14

Neurology

Characterization of Cln3p, the gene product responsible for juvenile neuronal ceroid lipofuscinosis, as a lysosomal integral membrane glycoprotein

Junji Ezaki, Mitsue Takeda‐Ezaki, Masato Koike, +7

Journal of Neurochemistry

Nitrated and Oxidized Products of a Single Tryptophan Residue in Human Cu,Zn-Superoxide Dismutase Treated with Either Peroxynitrite-Carbon Dioxide or Myeloperoxidase-Hydrogen Peroxide-Nitrite

Fumiyuki Yamakura, Takashi Matsumoto, Keiichi Ikeda, +7

The Journal of Biochemistry

Modification of a single tryptophan residue in human Cu,Zn-superoxide dismutase by peroxynitrite in the presence of bicarbonate

Fumiyuki Yamakura, Takashi Matsumoto, Tsutomu Fujimura, +4

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Zn-superoxide DismutaseBiochemistryNatural SciencesBioactive MetalSingle Tryptophan Residue +7

Reduction of insulin-stimulated glucose uptake by peroxynitrite is concurrent with tyrosine nitration of insulin receptor substrate-1

Takashi Nomiyama, Yasuhiro Igarashi, Hikari Taka, +11

Biochemical and Biophysical Research Communications

BiochemistryInsulin Receptor Substrate-1MedicineInsulin ManagementDiabetes +8