Shinji Saiki

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

Noriyuki Matsuda, Shigeto Sato, Kahori Shiba et al. · The Journal of Cell Biology · 2010 · 1.9K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Lysosomal positioning coordinates cellular nutrient responses

Viktor I. Korolchuk, Shinji Saiki, Maike Lichtenberg et al. · Nature Cell Biology · 2011 · 896 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

Andrea Williams, Sovan Sarkar, Paul A. Cuddon et al. · Nature Chemical Biology · 2008 · 786 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +14

Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition

Shinji Saiki, Yukiko Sasazawa, Yoko Imamichi et al. · Autophagy · 2011 · 419 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17

CHCHD2 mutations in autosomal dominant late-onset Parkinson's disease: a genome-wide linkage and sequencing study

Manabu Funayama, Kenji Ohe, Taku Amo et al. · The Lancet Neurology · 2015 · 359 citations

Life Sciences, Genetics, Molecular Genetics +12