Blood Advances · 2017 · 10 citations · 33 references
Life SciencesGeneticsMolecular BiologyGene ExpressionGene Expression DynamicsEpitope Tag Knock-inTransient Expression Systems
Key Points The new mouse strain C57BL/6N-Meis1em1Bcca can track the dynamic changes of MEIS1 expression by a GFP reporter and an HA epitope tag. This tagging strategy provides a platform to study the function and regulation of Meis1 as well as other transcription factors.
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Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong, F. Ann Ran, David Cox et al. · Science · 2013 · 15.7K citations
Genome engineering using the CRISPR-Cas9 system
F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text
Stem cell gene expression programs influence clinical outcome in human leukemia
Kolja Eppert, Katsuto Takenaka, Eric R. Lechman et al. · Nature Medicine · 2011 · 1K citations
Medicine, Cancer Biology, Oncology +16