Blood-derived amyloid-β protein induces Alzheimer’s disease pathologies

RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain

Rashid Deane, Shi Du Yan, Ram Kumar Submamaryan et al. · Nature Medicine · 2003 · 1.4K citations

Neurophysiology, Medicine, Amyloid-β Peptide Transport +7

Exogenous Induction of Cerebral ß-Amyloidogenesis Is Governed by Agent and Host

Melanie Meyer‐Luehmann, Janaky Coomaraswamy, Tristan Bolmont et al. · Science · 2006 · 937 citations · Full text

Brain Extracts, Immunology, Neurochemical Biomarkers +20

Co-expression of multiple transgenes in mouse CNS: a comparison of strategies

Joanna L. Jankowsky, Hilda H. Slunt, Tamara Ratovitski et al. · Biomolecular Engineering · 2001 · 822 citations

Knockout Mouse, Developmental Biology, Molecular Neuroscience +10

Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

D. J. Selkoe, Marcia B. Podlisny, Catharine Joachim et al. · Proceedings of the National Academy of Sciences · 1988 · 578 citations · Full text

Molecular Biology, Neurochemical Biomarkers, Progressive Cerebral Deposition +17

Cerebral amyloid angiopathy in the brains of patients with Alzheimer's disease

Ronald J. Ellis, John Olichney, L. J. Thal et al. · Neurology · 1996 · 558 citations