Concepedia

Amyloid Plaques

Amyloid Plaques is a neuropathological hallmark of aging and neurodegenerative disease characterized by extracellular deposits of misfolded amyloid-beta protein in the brain parenchyma, distinguished from other proteinopathies by its specific fibrillar composition and association with Alzheimer’s disease pathology.

11.4K

Publications

1.2M

Citations

45.4K

Authors

5.9K

Institutions

Publications per year

2017–2026

3.3K

Variants

Senile Plaques

Parents

Publications

11.4K

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

George G. Glenner, Caine W. Wong · Biochemical and Biophysical Research Communications · 1984 · 5.4K citations

, , +14

Lecanemab in Early Alzheimer’s Disease

Christopher H. van Dyck, Chad J. Swanson, Paul Aisen et al. · New England Journal of Medicine · 2022 · 5.2K citations · Full text

, , +17

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

Alison Goate, Marie‐Christine Chartier‐Harlin, Jeremy Brown et al. · Nature · 1991 · 4.6K citations

, , +16

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

Jie Kang, Hans-Georg Lemaire, Axel Unterbeck et al. · Nature · 1987 · 4.6K citations

, , +14

Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound‐B

William E. Klunk, Henry Engler, Agneta Nordberg et al. · Annals of Neurology · 2004 · 4.5K citations

, , +15

1–5 of 11.4K

Authors

45.4K

  1. BT
    Bradley T. Hyman

    Massachusetts General Hospital, United States

    147 publications · 32.9K citations

    92

    h-index

  2. DM
    David M. Holtzman

    Washington University in St. Louis, United States

    137 publications · 31K citations

    89

    h-index

  3. CL
    Colin L. Masters

    The University of Melbourne, Australia

    164 publications · 39.3K citations

    83

    h-index

  4. KB
    Kaj Blennow

    University of Gothenburg, Sweden

    165 publications · 18.9K citations

    75

    h-index

  5. CR
    Clifford R. Jack

    Mayo Clinic, United States

    123 publications · 16K citations

    64

    h-index

1–5 of 45.4K

Institutions

5.9K

  1. Harvard University

    Cambridge, United States

    156 h-index

    2.2K publications

    464.3K citations

  2. Massachusetts General Hospital

    Boston, United States

    142 h-index

    2.2K publications

    400.3K citations

  3. Washington University in St. Louis

    St Louis, United States

    118 h-index

    1.3K publications

    246.3K citations

  4. Brigham and Women's Hospital

    Boston, United States

    107 h-index

    850 publications

    191.6K citations

  5. University of Pennsylvania

    Philadelphia, United States

    99 h-index

    985 publications

    147K citations

  6. Mayo Clinic in Florida

    Jacksonville, United States

    94 h-index

    946 publications

    144.8K citations

  7. University of California San Diego

    San Diego, United States

    92 h-index

    721 publications

    166.8K citations

  8. University of California, San Francisco

    San Francisco, United States

    92 h-index

    826 publications

    128.5K citations

1–8 of 5.9K

Venues

  1. Journal of Neuroscience

    259 publications · 58.8K citations

    140

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 213 publications · 69.7K citations

    135

    h-index

  3. Journal of Biological Chemistry

    JBC · 266 publications · 44.3K citations

    118

    h-index

  4. Neurology

    267 publications · 44.2K citations

    109

    h-index

  5. Brain

    172 publications · 31.8K citations

    106

    h-index

1–5