RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease

Shi Du Yan, Xi Chen, Jin Fu, +11

Nature

Neurodegenerative DiseasesAlzheimer's DiseaseNeurologyNeuroscienceBrain Pathology +2

RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain

Rashid Deane, Shi Du Yan, Ram Kumar Submamaryan, +20

Nature Medicine

NeurophysiologyMedicineAmyloid-β Peptide TransportBlood-brain BarrierBrain-immune Interaction +5

The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses

Ann Marie Schmidt, Shi Du Yan, Shi Fang Yan, +1

Journal of Clinical Investigation

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

Heng Du, Lan Guo, Fang Fang, +12

Nature Medicine

Alzheimer's DiseaseCyclophilin D DeficiencyDementiaVascular DementiaNeurochemical Biomarkers +6

N ε-(Carboxymethyl)Lysine Adducts of Proteins Are Ligands for Receptor for Advanced Glycation End Products That Activate Cell Signaling Pathways and Modulate Gene Expression

Thomas Kislinger, Caifeng Fu, Birgit Huber, +8

Journal of Biological Chemistry

LRP/Amyloid β-Peptide Interaction Mediates Differential Brain Efflux of Aβ Isoforms

Rashid Deane, Zhenhua Wu, Abhay P. Sagare, +13

Neuron

Aβ IsoformsMolecular NeuroscienceProtein FoldingNeurochemical BiomarkersProtein Misfolding +4

Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues.

J Brett, Ann Marie Schmidt, Shi Du Yan, +7

PubMed

Mitochondrial Aβ: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease

Casper Caspersen, Ning Wang, Jun Yao, +7

The FASEB Journal

Cell DeathNeurochemical BiomarkersMitochondrial BiologyOxidative StressAlzheimer's Disease +20

Advanced Maillard reaction end products are associated with Alzheimer disease pathology.

Mark A. Smith, Shinji Taneda, Peggy L. Richey, +6

Proceedings of the National Academy of Sciences

Molecular BiologyNeurochemical BiomarkersAlzheimer Disease PathologyAlzheimer's DiseaseProtein Folding +15

Glycated tau protein in Alzheimer disease: a mechanism for induction of oxidant stress.

Shi Du Yan, Xi Chen, Ann Marie Schmidt, +7

Proceedings of the National Academy of Sciences

Sporadic Alzheimer DiseaseAgingMolecular BiologyNeurochemical BiomarkersTau Protein +18