STAR: ultrafast universal RNA-seq aligner

Alexander Dobin, Carrie Davis, Felix Schlesinger, +6

Bioinformatics

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

Lijun Sun, Jiaxi Wu, Fenghe Du, +2

Science

Molecular RegulationImmunologyMolecular BiologyInnate ImmunityTranscriptional Regulation +21

Full-length RNA-seq from single cells using Smart-seq2

Simone Picelli, Omid R. Faridani, Åsa K. Björklund, +3

Nature Protocols

Functional GenomicsSingle Cell SequencingMedicineRna SequencingSingle-cell Genomics +5

The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote

Yang Liao, Gordon K. Smyth, Wei Shi

Nucleic Acids Research

EngineeringGeneticsStructured DataGenomicsSequence Alignment +28

Tumor spectrum analysis in p53-mutant mice

Tyler Jacks, Lee Ann Remington, Bart O. Williams, +4

Current Biology

Tumor BiologyTumor HeterogeneityTumor Spectrum AnalysisMedicineCell Biology +1

Scater: pre-processing, quality control, normalization and visualization of single-cell RNA-seq data in R

Davis J. McCarthy, Kieran R. Campbell, Aaron T. L. Lun, +1

Bioinformatics

STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors

Seng‐Ryong Woo, Mercedes B. Fuertes, Leticia Corrales, +9

Immunity

Cancer ImmunosurveillanceInnate Immune SystemImmunologyTumor ImmunityImmunoediting +6

cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING

Andrea Ablasser, Marion Goldeck, Taner Cavlar, +6

Nature

Nucleic Acid ChemistrySignal TransductionMolecular PhysiologyBiochemistryNatural Sciences +4

Bayesian approach to single-cell differential expression analysis

Peter V. Kharchenko, Lev Silberstein, David T. Scadden

Nature Methods

Nuclear envelope rupture and repair during cancer cell migration

Céline Denais, Rachel M. Gilbert, Philipp Isermann, +7

Science