Adeline Fluteau

cGAS surveillance of micronuclei links genome instability to innate immunity

Karen J. Mackenzie, Paula Carroll, Carol-Anne Martin et al. · Nature · 2017 · 1.6K citations · Full text

Chromatin, Systems Biology, Genetics +8

CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions

Michal Zimmermann, Olga Murina, Martin A.M. Reijns et al. · Nature · 2018 · 402 citations · Full text

Natural Sciences, Genetics, Parp-trapping Lesions +10

Ribonuclease H2 mutations induce a <scp>cGAS</scp> / <scp>STING</scp> ‐dependent innate immune response

Karen J. Mackenzie, Paula Carroll, Laura A. Lettice et al. · The EMBO Journal · 2016 · 231 citations · Full text

Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions

Patricia Heyn, Clare V. Logan, Adeline Fluteau et al. · Nature Genetics · 2018 · 151 citations · Full text

Chromatin, Gain-of-function Dnmt3a Mutations, Developmental Biology +10

Mutations in genes encoding condensin complex proteins cause microcephaly through decatenation failure at mitosis

Carol-Anne Martin, Jennie Murray, Paula Carroll et al. · Genes & Development · 2016 · 143 citations · Full text

Mitophagy, Brain Development, Genetics +23